The Library's investigating a subscription to the Human Gene Mutation Database. HGMD pulls information from the literature about disease-causing mutations and disease-associated or functional polymorphisms for searching and display . You can use HGMD to find lists of disease-causing mutations within specific genes; lists of mutations that are known to cause specific diseases; lists of mutations of a certain type (e.g. A-C substitutions, microdeletions, etc.) in a certain gene or group of genes, or that cause a certain disease; and more. A trial is available until Friday, April 10 at http://portal.biobase-international.com - follow the link to HGMD (you must be on campus for this to work).
An older (about 3 years behind) version of the database is free for academic users; the most recent data is available at considerable cost. To judge whether there is enough interest to warrant the expense of a subscription, we’d like to hear your answers to any or all of the following questions:
Would the up-to-date (paid) version of HGMD be useful to your research?
Would it be substantially better than other resources that provide some of the same information (e.g. Entrez Gene, OMIM, the public version of HGMD)?
Does your lab already have a current subscription to HGMD? If so, it would be very useful for us to know which lab you are in, and how many researchers there are in your lab.
Please direct any feedback you have to Tina O’Grady, christina.ogrady@mssm.edu, 212-241-3990 (x43990). Thanks!